Skip 
Navigation Link
Medical Disorders
Resources
Basic InformationLookupsLatest News
Excess Weight May Raise Rosacea RiskDecline in Antibiotic Use in Livestock Isn't Enough, Critics SayCould a Hot Cup of Tea Preserve Your Vision?Breathing Retraining Beneficial in Patients With AsthmaZika Babies Facing Increasing Health Problems With AgeHealth Tip: Dental Association Supports Fluoridated WaterAnother Legacy of Terror Attacks: MigrainesRain May Not Cause Achy Joints After AllDisrupted Sleep Linked to Increased Amyloid-β ProductionAtherosclerosis ID'd in Many Without CV Risk FactorsArtificial Intelligence Promising for CA, Retinopathy DiagnosesFirst Drug Approved for Rare Condition That Inflames Blood VesselsProtecting Your Health From Wildfire SmokeHealth Tip: Recognize Warning Signs of HypothermiaNew Hope for Kids With Multiple Food AllergiesFew Patients, Providers Discuss Costs of Glaucoma Medicationsβ-Cell Sensitivity to Glucose Impaired After Gastric BypassHow to Perk Up the Holidays for Hospital PatientsVigorous Exercise May Help Slow Parkinson's DiseaseIf Mom Has Rheumatoid Arthritis, Baby May Develop It, TooNew Gene Therapy May Be Cure for 'Bubble Boy' DiseaseAnother Gene Therapy Breakthrough Against HemophiliaPrenatal Sugar Intake May Increase Asthma Risk in OffspringObesity May Be Tied to Higher Rosacea Risk in WomenGot Scabies? Here's What to DoAre Women With Parkinson's at a Disadvantage?Bariatric Surgery Alters Liver Fatty Acid MetabolismORBIT Bleeding Risk Score Performs Best in A-FibHealth Tip: Prevent the Spread of NorovirusAre Good Kidneys Going to Waste?Metabolic Risk Factors Linked to Severe Liver DiseaseImpaired White Matter Integrity for Depression in Parkinson'sHave Eczema? No Need for Bleach Baths, Study SuggestsPowerful Clot-Busting Drugs Not Useful After Leg Blockages: StudyComing Soon: A Gel That Could Help Save Soldiers' EyesGene Therapy May Allow Hemophilia Patients to Go Without MedsThyroidectomy-Specific Quality Improvement Measures ID'dPatients OK With Fewer Opioids After Gallbladder SurgeryShhhh! Patients Are SleepingDiagnostic Mutations ID'd in Chronic Kidney Disease PatientsAntithrombotics Deemed Safe in Carpal Tunnel Release SurgeryLink Between Diabetes, Antibiotic Use Called Into QuestionHealth Tip: Diagnosing PneumoniaNoisy Commutes Could Cause Long-Lasting DamageThe Buzz on How Flies Spread DiseaseRisk of Surgical Complications Up for Overlapping Hip SurgeryOral Microbiome Composition Linked to Esophageal Cancer RiskSmartphone Pics Help Docs ID Kids' Skin ConditionEven Non-Heart Surgery May Harm Your HeartCan Scrotal Vein Condition Hike Heart Risks?
Questions and AnswersLinksBook Reviews
Related Topics

Coming Soon: A Faster Test for Antibiotics Against UTIs?

HealthDay News
by -- Randy Dotinga
Updated: Oct 4th 2017

new article illustration

WEDNESDAY, Oct. 4, 2017 (HealthDay News) -- Urinary tract infections (UTIs) plague millions of Americans each year. Now, researchers say they've developed a test that can tell in minutes whether or not a particular antibiotic can clear up the problem.

The issue is an important one, doctors say, since many of the bacteria behind UTIs have grown resistant to certain antibiotics. And, left untreated, these infections can have serious effects, especially in the frail and elderly.

"We live in an era of multidrug-resistant bacteria, so-called 'superbugs' that can cause life-threatening infections," said infectious disease specialist Dr. Sunil Sood, who reviewed the new study.

"Modern molecular techniques to distinguish bacteria that are resistant from those that are susceptible to common antibiotics could be lifesaving," said Sood. He is chair of pediatrics at Northwell Health's Southside Hospital in Bay Shore, N.Y.

According to the study authors, current urine tests can rapidly spot a UTI, but it can still take days for the exact germs -- and the proper antibiotic to use against them -- to be identified.

In the new study, researchers led by Nathan Schoepp, of the California Institute of Technology, developed a new way of analyzing germs in urine samples. Instead of isolating germs and waiting for them to grow, the researchers used a "DNA amplification" technique to analyze the bacteria's genome, or "genetic blueprint."

The investigators tested the new screen out on 51 urine samples containing either antibiotic-resistant or antibiotic-susceptible strains of bacteria.

Reporting in the Oct. 4 issue of Science Translational Medicine, Schoepp's team said the new test can render results in less than 30 minutes. Those results confirmed that urine samples held germs that were either susceptible or resistant to two common antibiotics: ciprofloxacin (Cipro) and nitrofurantoin (Macrobid, Furadantin and Macrodantin).

According to the researchers, the test might also prove useful in other areas of treatment of infectious disease.

Sood said that, if this work pans out, it could be a real advance in care.

"The technique used by Schoepp and colleagues has the potential to identify such bacteria within the time frame of an office or emergency room visit," he explained. "If further developed, this method could help doctors to more rapidly treat infections with the right antibiotics."

Dr. Howard Selinger directs family medicine at Quinnipiac University's Frank D. Netter MD School of Medicine in Hamden, Conn. He agreed that the new test could speed care, but said cost is a concern, too.

"We must demonstrate that directed therapy delivers better value, by improving quality and lowering overall cost," Selinger said. "This will allow for insurance coverage and not cause patients to bear the brunt of the cost of this new technology."

More information

There's more on UTIs at the U.S. National Institute of Diabetes and Digestive and Kidney Diseases.