Skip 
Navigation Link
Sleep Disorders
Resources
Basic InformationLatest News
AAIC: Alzheimer Biomarkers Up With Sleep Disordered BreathingCPAP Mask Not a Prescription for Heart TroublesHealth Tip: Get the Facts on Alcohol and SleepHealth Tip: If You Have Sleep ApneaSleep Apnea Linked to Diabetic Retinopathy in Type 2 DiabetesSLEEP: Helpful Hints From Bed Partner Can Exacerbate InsomniaBed Partner Often Fuels Loved One's InsomniaLoneliness May Lead to Sleepless NightsWarming Climate, More Sleepless Nights?Sleepless Nights Could Pose Heart Risk DangersSleep Apnea Reporting Low Among Individuals Aged ≥65Sleep Apnea May Boost Odds of Irregular HeartbeatDocs May Not Spot Sleep Apnea, Insomnia in BlacksSleep Apnea May Boost Pregnancy ComplicationsSleepless Nights, Unhealthy Hearts?Curbing Sleep Apnea Might Mean Fewer Night Trips to BathroomHealth Tip: Slipping Back Into SleepPast Prescribing Behavior Predicts Choice of Insomnia RxWhat Guides Docs' Sleeping Pill Picks? 'Same Old Same Old,' Study SaysSkimp on Sleep and You Just May Wind Up SickSleepless Nights Linked to Asthma Later in LifeThe ABCs of Good ZzzzzsLevel 3 Polysomnography Data Noninferior for OSAJury Still Out on Whether to Screen All Adults for Sleep ApneaHealth Tip: 5 Things to Help You Sleep SoundlyMany Misuse OTC Sleep Aids: SurveyHomeless, And Often Sleepless TooHealth Tip: Struggling in the Morning?VA ECHO Program Feasible for Management of Sleep DisordersStudy Finds Genetic Link Between Sleep Problems and ObesityStudy Sees Link Between Insomnia, AsthmaWeb-Based Help for Insomnia Shows PromiseHealth Tip: When Sleep is InterruptedCPAP Improves Asthma Control, QoL for Adults With Asthma, OSASleep Apnea May Boost Risk for Post-Op ProblemsHome-Based CBT Program for Sleep Feasible in PregnancyHealth Tip: Making the Transition to SleepSleep Troubles, Heart Troubles?Why Some Women Find Good Sleep Tough to GetSleep Apnea Diagnoses Up Among Outpatients From 1993 to 2010For Those With Sleep Apnea, Maybe It's Time for a Driving TestMouse Study Suggests Brain Circuit Involved in Sleep-Wake CycleRisk of Cardiovascular Events Not Reduced With CPAP UseNighttime Sleep Disturbance Common in Chronic PainResistant Hypertension Linked to Increased Risk of Sleep ApneaDrowsy Driving Causes 1 in 5 Fatal Crashes: ReportStudy Links Sleep Problems to Stroke Risk, RecoveryAssociated Professional Sleep Societies, June 5-9, 2010Sleep Disorder News Feed
Questions and AnswersLinksBook Reviews
Related Topics

Medical Disorders
Mental Disorders

Risk of Cardiovascular Events Not Reduced With CPAP Use


HealthDay News
Updated: Aug 30th 2016

new article illustration

TUESDAY, Aug. 30, 2016 (HealthDay News) -- While treatment with continuous positive airway pressure (CPAP) reduces sleep apnea symptoms, it does not lower users' long-term odds for cardiovascular events, according to a study published online Aug. 28 in the New England Journal of Medicine. The research was published to coincide with the annual European Society of Cardiology Congress, held from Aug. 27 to 31 in Rome.

Doug McEvoy, M.D., a clinician at the Adelaide Institute for Sleep Health at Flinders University in Australia, and colleagues selected 2,717 patients with moderate-to-severe sleep apnea from 89 clinical centers across seven countries. Most were older males (average age 61), and were overweight, habitual snorers. All had been diagnosed with some form of cardiovascular disease. About half the participants were randomly chosen to receive CPAP, while the others received standard cardiovascular disease care plus advice on trying to maintain healthy sleep without CPAP.

The team found no differences between CPAP users and non-users in rates for heart-related death, myocardial infarction or stroke or transient ischemic attack, or hospitalization for heart failure. For example, 17.0 percent of patients in the CPAP group had a serious cardiovascular event, compared to 15.4 percent of non-users (hazard ratio with CPAP, 1.10; 95 percent confidence interval, 0.91 to 1.32; P = 0.34). CPAP users reported reductions in daytime sleepiness, a boost in health-related quality of life, fewer work days lost, and better mood, with less risk of depression.

McEvoy believes that prior observational studies may have "overestimated" the link between sleep apnea and cardiovascular outcomes. Another factor might be that many participants could only use CPAP about three hours a night. McEvoy pointed out that the study participants who were able to use the treatment even a bit longer -- four or more hours -- did show "a trend toward a reduction in stroke." All of this suggests that "better-tolerated obstructive sleep apnea therapies, or new ways of making CPAP more tolerable, may be needed before a benefit of [the] treatment on cardiovascular outcomes can be shown," he told HealthDay.

The study was funded in part by Philips Respironics; several authors disclosed financial ties to the pharmaceutical and medical device industries.

Abstract
Full Text
Editorial
More Information